There are at least five known forms of ritonavir, not just two.

A tiny bit of Form II ritonavir acted as a nucleation site, lowering the activation energy and causing all Form I to crystallize into Form II, with seed crystals spreading through the air.

Ritonavir was introduced in 1996 to treat HIV.

By 1998, 75,000 patients across the US were taking ritonavir daily.

Abbott needed to halt all production of ritonavir immediately due to the quality control issues.

Abbott stated that the semi-solid formulation of ritonavir began to change into a crystal form, a transformation they believed was a scientific and chemical impossibility.